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中文人类
SH3BP2 - SH3 Domain Binding Protein 2
Alias:
3BP2
CRBM
CRPM
3BP-2
RES4-23
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这个基因编码的蛋白质具有N端pleckstrin同源性(PH)结构域，一个SH3结合脯氨酸丰富区域，以及一个C端的SH2结构域。该蛋白质与几种蛋白质的SH3结构域结合，包括ABL1和SYK酪氨酸激酶，并作为细胞质接头蛋白，正向调节T细胞、自然杀伤(NK)和嗜碱性细胞中的转录活性。这个基因的突变导致天使面谱。已经发现这个基因的多个转录变异体，编码不同的异构体。[RefSeq，2009年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SH3BP2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
