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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
SGK1 - Serum/glucocorticoid Regulated Kinase 1
Alias:
SGK
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种丝氨酸/苏氨酸蛋白激酶,在细胞应激反应中扮演重要角色。这个激酶激活某些钾、钠和氯通道,暗示其参与细胞存活、神经元兴奋性和肾钠排泄等过程的调节。这个基因的高表达可能参与高血压和糖尿病肾病的发病。已注意到这个基因有几个可变剪接的转录变异体,编码不同的异构体。[由RefSeq,2009年1月提供]
Related ID:
NCBI:6446
ENSEMBL:ENSG00000118515
HGNC:10810
UNIPROT:O00141
OMIM:602958
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6446
5
14
148857 bp
48.94
13
--
7
59
SGK1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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