大鼠

Isl1 - ISL LIM homeobox 1

Alias:
Isl-1
isl-1=homeobox
Favorite
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性为RNA聚合酶II;RNA聚合酶II顺式调控区域序列特异性DNA结合活性;以及雌激素受体的结合活性。参与几个过程,包括细胞对糖皮质激素刺激的应答;细胞内雌激素受体信号通路负调控;以及胰岛素分泌的正调控。位于细胞核中。这个基因的人类同源物与1型糖尿病和2型糖尿病有关。与人类ISL1(ISL LIM同源盒1)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
3
6
11293 bp
39.04
15
2

Isl1 Genetics information (-)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Sequence
Comparison
Al agent
Tutorials
Back to top