人类

RGS18 - Regulator Of G Protein Signaling 18

Alias:
RGS13
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码调节G蛋白信号转导家族的一个成员。这个蛋白质包含一个保守的、120个氨基酸组成的叫做RGS域的结构域。这个蛋白质通过与激活的、结合GTP的G alpha亚基结合,并作为GTP酶激活蛋白(GAP)发挥作用,增加GTP转化为GDP的速率。这种水解允许G alpha亚基与G beta/gamma亚基异二聚体结合,形成无活性的G蛋白异三聚体,从而终止信号。这个基因的转录剪接变体已经被观察到,但还没有被彻底鉴定。[由RefSeq提供,2008年7月]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
5
27354 bp
27.58
9
--
4
6

RGS18 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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