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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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PGA4 - Pepsinogen A4
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码消化酶胃蛋白酶的前体,是内肽酶A1家族的成员。编码的前体被胃主细胞分泌,并在酸性条件下经历自催化切割,形成具有活性的酶,用于消化饮食中的蛋白质。这个基因位于染色体11上的一组相关基因中,每个基因编码多种胃蛋白酶原之一。血清中胃蛋白酶原水平可能作为萎缩性胃炎和胃癌的生物标志物。[RefSeq,2015年7月提供]
Related ID:
NCBI:643847
ENSEMBL:ENSG00000229183
HGNC:8886
UNIPROT:P0DJD7
OMIM:169720
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
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Reference
643847
1
9
9348 bp
41.98
3
--
2
10
PGA4 Genetics information (+)
GRCh38
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* This data comes from NCBI.
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