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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Sirt3 - sirtuin 3
Alias:
Sir2l3
2310003L23Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有依赖NAD的组蛋白去乙酰化活性(特异性的H3-K14)和序列特异性的DNA结合活性。参与肽基-赖氨酸去乙酰化;鞘氨醇生物合成过程的正向调节;以及线粒体转录的正向调节。在肽基-赖氨酸乙酰化和蛋白质去乙酰化的负向调节的上游或内部发挥作用。位于线粒体内膜和线粒体基质中。作为含蛋白质复合物的一部分。在包括大脑;鳃弓;内分泌腺;生殖泌尿系统;以及肝和胆道系统在内的几个结构中表达。用于研究腹部肥胖-代谢综合症。与人类的SIRT3(sirtuin 3)正交所知。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:64384
ENSEMBL:ENSMUSG00000025486
UNIPROT:Q8R104
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
64384
5
7
18647 bp
36.62
14
18
Sirt3 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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Name
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