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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Sirt2 - sirtuin 2
Alias:
Sir2l
SIR2L2
5730427M03Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活β微管蛋白结合活性;组蛋白脱乙酰酶活性;和微管蛋白脱乙酰酶活性。参与几个过程,包括细胞周期过程的正向调节;蛋白质脱乙酰化;和RNA聚合酶II的转录调节。在组蛋白脱乙酰化、NLRP3炎症小体复合物组装的负向调节和脂肪细胞分化的调节中起上游作用或位于其中。位于几个细胞成分中,包括Schmidt-Lanterman沟;节段旁连接;和核周体。在早期概念体;眼睛;卵母细胞;耳窝;和躯干肢板中表达。与人类的SIRT2(sirtuin 2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:64383
ENSEMBL:ENSMUSG00000015149
UNIPROT:Q8VDQ8
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
64383
4
16
21895 bp
43.26
11
24
Sirt2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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Cell-specific RNA expression
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Name
MGI
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