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中文人类
SPINK9 - Serine Peptidase Inhibitor Kazal Type 9
Alias:
LEKTI2
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这个基因编码的蛋白质是一种Kazal型丝氨酸蛋白酶抑制剂，似乎特异性地针对手掌-脚掌表皮中的激肽酶相关肽酶5（KLK5）。KLK5是皮肤脱落的重要启动子，因此编码的蛋白酶抑制剂可能调节手掌上皮和脚底皮的分化。这种阳离子蛋白质还通过激活表皮生长因子受体（EGFR）促进角化细胞的迁移。[RefSeq,2015年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SPINK9 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
