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中文人类
NFKBIZ - NFKB Inhibitor Zeta
Alias:
IKBZ
INAP
MAIL
ikB-zeta
ikappaBzeta
IkappaB-zeta
I-kappa-B-zeta
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这个基因是锚重复家族的一员，并被脂多糖（LPS）诱导。编码产物的C端部分含有锚重复序列，与I kappa B家族蛋白质具有高度序列相似性。已知后者通过锚重复结构域与NF-kappa B蛋白质相互作用，在LPS的炎症反应中发挥作用。研究表明，这个基因产物是核I kappa B蛋白质之一，并且是IL-6产生的激活剂。已经发现这个基因有两个转录变异体，编码不同的异构体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
NFKBIZ Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
