人类

PDLIM2 - PDZ And LIM Domain 2

Alias:
SLIM
MYSTIQUE
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码PDZ-LIM结构域蛋白质的ALP亚家族成员。编码的蛋白质通过PDZ结构域与肌动蛋白细胞骨架相互作用,抑制附着依赖性生长并促进细胞迁移和粘附。该编码蛋白质也是一种潜在的肿瘤抑制蛋白,这个基因的表达减少与包括乳腺癌和成人T细胞白血病在内的几种恶性肿瘤有关。已经观察到这个基因的替代剪接转录变异体编码多种异构体。[RefSeq,2011年10月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
9
19286 bp
37.46
44
--
3
8

PDLIM2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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