人类

SFRP1 - Secreted Frizzled Related Protein 1

Alias:
FRP
FRP1
FrzA
FRP-1
SARP2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码SFRP家族的一员,该家族包含一个与假定的Frizzled蛋白Wnt结合位点同源的富含半胱氨酸的结构域。这个家族的成员作为Wnt信号的可溶性的调节物发挥作用;SFRP基因的表观遗传沉默导致Wnt途径的失调激活,这与癌症有关。这个基因也可能参与决定视网膜中光感受器细胞的极性。[RefSeq,2009年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
3
47512 bp
35.39
15
--
9
7

SFRP1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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