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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
SFRP1 - Secreted Frizzled Related Protein 1
Alias:
FRP
FRP1
FrzA
FRP-1
SARP2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码SFRP家族的一员,该家族包含一个与假定的Frizzled蛋白Wnt结合位点同源的富含半胱氨酸的结构域。这个家族的成员作为Wnt信号的可溶性的调节物发挥作用;SFRP基因的表观遗传沉默导致Wnt途径的失调激活,这与癌症有关。这个基因也可能参与决定视网膜中光感受器细胞的极性。[RefSeq,2009年9月提供]
Related ID:
NCBI:6422
ENSEMBL:ENSG00000104332
HGNC:10776
UNIPROT:Q8N474
OMIM:604156
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6422
1
3
47512 bp
35.39
15
--
9
7
SFRP1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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No data available
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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Name
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