Log In|Sign Up
中文人类
CRLF2 - Cytokine Receptor Like Factor 2
Alias:
CRL2
TSLPR
CRLF2Y
Favorite
这个基因编码I型细胞因子受体家族的一员。编码的蛋白质是胸腺基质淋巴细胞生成素(TSLP)的受体。与白细胞介素7受体(IL7R)一起，编码的蛋白质和TSLP激活STAT3、STAT5和JAK2通路，这些通路控制诸如细胞增殖和造血系统发育等过程。这个基因与染色体14上的免疫球蛋白重链基因(IGH)或同一X或Y染色体上的P2Y嘌呤受体8基因(P2RY8)重排与B祖急性淋巴细胞白血病(ALL)和Down综合征ALL有关。已经发现了这个基因的可变剪接转录变异体。[由RefSeq，2014年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CRLF2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
