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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Popdc2 - popeye domain containing 2
Alias:
Pop2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个含有Popeye结构域的膜蛋白家族成员。这个家族的蛋白质包含三个螺旋跨膜结构域和一个保守的细胞内Popeye结构域。在成年小鼠中,这个基因在心肌细胞中表达水平很高,缺乏这个基因的小鼠会发生应激诱导的心动过速功能障碍。这个蛋白与一个二孔域钾通道结合并将其招募到质膜上。环状腺苷酸通过Popeye结构域负调控这个相互作用。可变剪接导致多个转录变异体。[RefSeq,2015年3月提供]
Related ID:
NCBI:64082
ENSEMBL:ENSMUSG00000022803
UNIPROT:Q9ES82
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
64082
5
4
16056 bp
41.25
3
5
Popdc2 Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
Gene Expression
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Name
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