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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Casp8 - caspase 8
Alias:
CASP-8
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
半胱氨酸型内肽酶活性;死亡受体结合活性;肿瘤坏死因子受体结合活性。参与几个过程,包括雌二醇反应;乙醇反应;和脂多糖反应。位于几个细胞成分中,包括细胞体;胞质;和膜筏。是CD95诱导死亡信号复合物的一部分。用于研究癌前肿瘤。几种疾病的生物标志物,包括心脏病(多种);肾脏病(多种);视网膜脱离;坐骨神经病;和癫痫状态。该基因的人类同源物与2B型自身免疫性淋巴增生综合症;乳腺癌;内分泌腺癌(多种);食管腺癌;和原发性免疫缺陷病有关。与人类CASP8(caspase 8)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:64044
ENSEMBL:ENSRNOG00000012331
UNIPROT:Q9JHX4
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
64044
5
9
48680 bp
55.34
32
4
Casp8 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Cell-specific RNA expression
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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