Ccnd2 - cyclin D2

Enables protein kinase binding activity. Involved in several processes, including cellular response to insulin stimulus; response to estradiol; and response to testosterone. Predicted to be located in chromatin; cytosol; and nucleus. Predicted to be part of cyclin D2-CDK4 complex. Predicted to be active in cytoplasm and nucleus. Used to study transitional cell carcinoma. Biomarker of colon cancer; glaucoma; impotence; and nephritis. Human ortholog(s) of this gene implicated in ductal carcinoma in situ; invasive lobular carcinoma; prostate cancer; and transitional cell carcinoma. Orthologous to human CCND2 (cyclin D2). [provided by Alliance of Genome Resources, Apr 2022]