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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
SELP - Selectin P
Alias:
CD62
GRMP
PSEL
CD62P
GMP140
LECAM3
PADGEM
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个140kDa的蛋白质,存在于血小板的alpha颗粒和内皮细胞的Weibel-Palade体中。这个蛋白质在血小板激活和脱颗粒过程中重新分布到质膜上,并调节激活的内皮细胞或血小板与白细胞之间的相互作用。这个膜蛋白是一个依赖于钙的受体,能够结合中性粒细胞和单核细胞的Lewis血型糖抗原的唾液酸形式。可能存在替代剪接变体,但记录较少。[由RefSeq,2008年7月提供]
Related ID:
NCBI:6403
ENSEMBL:ENSG00000174175
HGNC:10721
UNIPROT:P16109
OMIM:173610
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
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Related Mouse Models
Reference
6403
7
17
41276 bp
90.82
50
--
6
19
SELP Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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No data available
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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