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中文人类
NECAB3 - N-terminal EF-hand Calcium Binding Protein 3
Alias:
NIP1
XB51
STIP3
EFCBP3
SYTIP2
APBA2BP
dJ63M2.4
dJ63M2.5
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这个基因编码的蛋白质与神经元特异性的X11-样蛋白（X11L）的氨基端结构域相互作用，通过非竞争性机制抑制X11L与淀粉样前体蛋白的结合，并消除X11L对β-淀粉样蛋白产生的抑制。这个蛋白质与X11L一起可能在淀粉样前体蛋白代谢和β-淀粉样蛋白生成的调节系统中发挥重要作用。该蛋白质被NIMA相关表达激酶2磷酸化，并定位在高尔基体上。已发现这个基因有多个编码不同异型的转录变异体。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
NECAB3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
