人类

SDC1 - Syndecan 1

Alias:
SDC
CD138
SYND1
syndecan
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种跨膜(I型)肝素硫酸蛋白多糖,是合成糖蛋白家族的一员。Syndecans调节细胞结合、细胞信号传递和细胞骨架组织,并且Syndecan受体是HIV-1 tat蛋白内化的必需成分。Syndecan-1蛋白作为整合膜蛋白发挥作用,并通过其与细胞外基质蛋白受体的参与,参与细胞增殖、细胞迁移和细胞-基质相互作用。已经检测到Syndecan-1表达的改变存在于几种不同的肿瘤类型中。虽然这个基因可能存在几个转录变异体,但迄今为止只描述了两个全长变异体。这两个变异体代表了这个基因的主要变异体,并编码相同的蛋白质。[RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5
5
24679 bp
32.46
18
--
4
15

SDC1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top