人类

CXCL11 - C-X-C Motif Chemokine Ligand 11

Alias:
IP9
H174
IP-9
b-R1
I-TAC
SCYB11
SCYB9B
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
化学诱引素是一组小的(大约8到14kD),主要碱性,结构上相关的分子,它们通过与其他7-跨膜,G蛋白耦合受体子集相互作用,调节各种类型的白细胞的细胞运动。化学诱引素在免疫系统的发育,稳态和功能中也起着基本作用,它们对中枢神经系统细胞以及参与血管生成的内皮细胞也有影响。化学诱引素分为两个主要亚家族,CXC和CC。这个抗菌基因是化学诱引素超家族的一个CXC成员。其编码的蛋白质在激活的T细胞中诱导化学趋化反应,并作为CXCR-3的主要配体。编码这种蛋白质的基因包含4个外显子,并至少有三个聚腺苷酸化信号,这可能反映了表达的手机器特异性调节。IFN-γ是这种基因的强有力的转录诱导剂。已经发现这种基因有两个转录变异体,编码不同的异构体。[由RefSeq,2014年10月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
4
2389 bp
10.37
5
--
--
11

CXCL11 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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