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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
BID - BH3 Interacting Domain Death Agonist
Alias:
FP497
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种死亡激动剂,它可以与激动剂BAX或拮抗剂BCL2异源二聚化,从而调节细胞凋亡。编码的蛋白质是BCL-2家族细胞死亡调节蛋白的一员。它是由caspase-8 (CASP8)诱导的线粒体损伤的中介;CASP8切割这个编码蛋白质的COOH-端部分,并将其转运到线粒体,触发细胞色素c的释放。已经发现了多种可变剪接转录变异体。[由RefSeq,2020年8月提供]
Related ID:
NCBI:637
ENSEMBL:ENSG00000015475
HGNC:1050
UNIPROT:P55957
OMIM:601997
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
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Reference
637
7
6
40528 bp
22.00
14
--
6
21
BID Genetics information (-)
GRCh38
Sequence Homology
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* This data comes from NCBI.
Gene Expression
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