人类

CCL23 - C-C Motif Chemokine Ligand 23

Alias:
CKb8
MIP3
Ckb-8
MIP-3
MPIF-1
SCYA23
Ckb-8-1
hmrp-2a
CK-BETA-8
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是位于17号染色体q臂上的一组化学因子基因之一。化学因子组成一个涉及免疫调节和炎症过程的分泌蛋白质超家族。该超家族根据成熟肽的N端半胱氨酸残基排列分为四个亚家族。这个化学因子是CC亚家族的一员,在静止的T淋巴细胞和单核细胞上显示趋化活性,对中性粒细胞活性较低,对激活的T淋巴细胞没有活性。该蛋白质还是多能造血祖细胞系集落形成的强力抑制剂。此外,这个基因的产物是趋化因子(C-C基序)受体1的强力激动剂。选择性剪接导致编码不同异型体的多种转录变异体。[RefSeq,2013年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
4
4915 bp
13.44
12
--
8
8

CCL23 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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