人类

CCL21 - C-C Motif Chemokine Ligand 21

Alias:
ECL
SLC
CKb9
TCA4
6Ckine
SCYA21
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这种抗菌基因是位于染色体9p臂上的几个CC细胞因子基因之一。细胞因子是一类参与免疫调节和炎症过程的分泌蛋白质家族。CC细胞因子是以两个相邻的半胱氨酸为特征的蛋白质。与其他趋化因子相似,这个基因编码的蛋白质抑制血细胞生成并刺激趋化作用。这个蛋白质在体外对胸腺细胞和激活的T细胞有趋化作用,但对B细胞、巨噬细胞或中性粒细胞没有趋化作用。这个基因编码的细胞因子也可能在调节淋巴细胞归巢到二级淋巴器官中发挥作用。它是趋化因子受体7的高亲和力功能性配体,该受体在T和B淋巴细胞上表达,并作为细胞因子家族的另一成员(小诱导性细胞因子A19)的已知受体。[RefSeq,2014年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
4
1132 bp
14.65
6
--
1
12

CCL21 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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