人类

BGN - Biglycan

Alias:
PGI
MRLS
DSPG1
PG-S1
SEMDX
SLRR1A
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码富含亮氨酸的小蛋白聚糖(SLRP)家族成员。编码的前原蛋白在蛋白水解过程中被加工成成熟蛋白,该成熟蛋白在多个组织的骨生长、肌肉发育和再生以及胶原纤维组装中发挥作用。该蛋白还可能调节炎症和先天免疫。此外,编码的蛋白可能参与人类患者的动脉粥样硬化和主动脉瓣狭窄。这个基因和相关基因decorin被认为是基因重复的结果。[RefSeq, Nov 2015提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
8
14567 bp
41.65
256
6
7
14

BGN Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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