人类

S100A8 - S100 Calcium Binding Protein A8

Alias:
P8
MIF
NIF
CAGA
CFAG
CGLA
L1Ag
MRP8
CP-10
MA387
60B8AG
S100-A8
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是S100蛋白质家族的一员,含有2个EF手钙结合结构域。S100蛋白质定位在广泛细胞的细胞质和/或细胞核中,并参与许多细胞过程的调节,如细胞周期进展和分化。S100基因包括至少13个成员,位于染色体1q21上的一个簇中。这个蛋白质可能具有抑制酪蛋白激酶和作为细胞因子的功能。这个蛋白质的表达改变与疾病囊性纤维化有关。已经发现这个基因有多个转录变异体,编码不同的异构体。[由RefSeq,2016年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5
3
32552 bp
10.84
11
--
8
43

S100A8 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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