人类

RYK - Receptor Like Tyrosine Kinase

Alias:
JTK5
RYK1
JTK5A
D3S3195
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种生长因子受体蛋白酪氨酸激酶家族的异常成员,在激活和核苷酸结合结构域中的多个保守残基处与其他成员不同。这个基因产物属于一个亚家族,其成员似乎不受激活区段的磷酸化调控。有研究表明,通过一种尚未确定的机制,招募信号功能辅助蛋白来介导生物学活性可能发生。编码的蛋白质具有富含亮氨酸的细胞外结构域,具有WIF型Wnt结合区域,一个单跨膜结构域,和一个细胞内的酪氨酸激酶结构域。这个蛋白质参与刺激Wnt信号通路,如轴突路径的调节。选择性剪接导致多个转录变异体,编码不同的异构体。[RefSeq,2012年2月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
15
93727 bp
67.81
17
--
5
9

RYK Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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