Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
人类
RYK - Receptor Like Tyrosine Kinase
Alias:
JTK5
RYK1
JTK5A
D3S3195
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种生长因子受体蛋白酪氨酸激酶家族的异常成员,在激活和核苷酸结合结构域中的多个保守残基处与其他成员不同。这个基因产物属于一个亚家族,其成员似乎不受激活区段的磷酸化调控。有研究表明,通过一种尚未确定的机制,招募信号功能辅助蛋白来介导生物学活性可能发生。编码的蛋白质具有富含亮氨酸的细胞外结构域,具有WIF型Wnt结合区域,一个单跨膜结构域,和一个细胞内的酪氨酸激酶结构域。这个蛋白质参与刺激Wnt信号通路,如轴突路径的调节。选择性剪接导致多个转录变异体,编码不同的异构体。[RefSeq,2012年2月提供]
Related ID:
NCBI:6259
ENSEMBL:ENSG00000163785
HGNC:10481
UNIPROT:P34925
OMIM:600524
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6259
2
15
93727 bp
67.81
17
--
5
9
RYK Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top