Cxcl6 - C-X-C motif chemokine ligand 6

Enables chemokine activity. Involved in several processes, including cellular response to lipopolysaccharide; positive regulation of receptor signaling pathway via JAK-STAT; and response to gamma radiation. Located in extracellular space. Used to study colon carcinoma. Biomarker of prostatitis and severe acute respiratory syndrome. Human ortholog(s) of this gene implicated in idiopathic pulmonary fibrosis. Orthologous to several human genes including CXCL6 (C-X-C motif chemokine ligand 6). [provided by Alliance of Genome Resources, Apr 2022]