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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Gucy1a1 - guanylate cyclase 1, soluble, alpha 1
Alias:
Gucy1a3
sGC-alpha1
GCS-alpha-1
GCS-alpha-3
1200016O07Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能激活鸟苷酸环化酶活性和离子结合活性。预测能对腺苷酸环化酶活性和胞苷酸环化酶活性做出贡献。参与由一氧化氮调节的逆突触信号传递,调节突触传递。在几个过程的上游或内部发挥作用,包括cGMP生物合成过程;一氧化氮介导的信号传导的正调控;和血管相关平滑肌的松弛。位于GABA能突触和谷氨酸能突触中。在几个结构中表达,包括消化系统;大脑;生殖泌尿系统;感光器官;和骨架。用于研究原发性开角型青光眼。该基因的人类同源物与Moyamoya病有关。与人类GUCY1A1(可溶性亚基α1的鸟苷酸环化酶1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:60596
ENSEMBL:ENSMUSG00000033910
UNIPROT:Q9ERL9
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
60596
3
9
53520 bp
77.59
5
4
Gucy1a1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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