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中文大鼠
Grm8 - glutamate metabotropic receptor 8
Alias:
Glur8
mGlur
Gprc1h
Mglur8
mGluR8b
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激活III组代谢型谷氨酸受体活性。参与检测机械刺激，涉及疼痛的感官感知；谷氨酸能突触传递；以及调节突触囊泡外泌。位于神经元突起；神经元细胞体；和前膜突触。是质膜的整合成分。在GABA能突触和谷氨酸能突触中活性。是前突触活性区膜的整合成分。用于研究帕金森病；癫痫；和视觉癫痫。这个基因的人类同源物与注意力缺陷多动障碍；自症障碍；和精神分裂症有关。与人类的GRM8（谷氨酸代谢型受体8）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Grm8 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
