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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
RNF4 - Ring Finger Protein 4
Alias:
SLX5
SNURF
RES4-26
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质含有RING指结构并作为转录调节因子。该蛋白质已被证明与TRPS1相互作用并抑制其活性,TRPS1是GATA介导的转录的抑制子。研究发现,转录抑制子ZNF278/PATZ与这种蛋白质相互作用,从而降低这种蛋白质对雄激素受体依赖的转录的增强作用。小鼠和大鼠的对应研究提示这种蛋白质在精子发生中具有作用。这个基因的一个假基因位于染色体1上。[由RefSeq,2010年7月提供]
Related ID:
NCBI:6047
ENSEMBL:ENSG00000063978
HGNC:10067
UNIPROT:P78317
OMIM:602850
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
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Reference
6047
4
8
46752 bp
21.32
8
--
6
19
RNF4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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* This data comes from NCBI.
Gene Expression
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