Tgm1 - transglutaminase 1

Predicted to enable identical protein binding activity and protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in several processes, including keratinocyte differentiation; peptide cross-linking; and positive regulation of keratinocyte proliferation. Predicted to act upstream of or within animal organ morphogenesis. Predicted to be located in adherens junction and membrane. Predicted to be intrinsic component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1. Orthologous to human TGM1 (transglutaminase 1). [provided by Alliance of Genome Resources, Apr 2022]