人类

RGS4 - Regulator Of G Protein Signaling 4

Alias:
RGP4
SCZD9
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
G蛋白信号调节因子(RGS)家族成员是作为Gα亚基的GTP酶激活蛋白(GAPs)的调节分子。RGS蛋白能够使Giα、Goα和Gqα亚型的G蛋白亚基去活化,使其进入其无活性的GDP结合形式。G蛋白信号调节因子4属于这个家族。所有RGS蛋白共享一个保守的120个氨基酸序列,称为RGS结构域。G蛋白信号调节因子4蛋白与RGS1有37%的相同性,与大鼠Rgs4有97%的相同性。这个蛋白负向调节异源三聚G蛋白上游或水平的信号传导,并定位在细胞质中。已发现这个基因的替代剪接转录变异体。[RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
5
7932 bp
23.26
12
--
11
9

RGS4 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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