人类

RFC5 - Replication Factor C Subunit 5

Alias:
RFC36
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码复制因子C复合物中最小的亚基,该复合物由五个不同的亚基(140、40、38、37和36千道尔顿)组成,并且是DNA复制所必需的。这个亚基与增殖细胞核抗原的C端区域相互作用,并在S期期间打开并将增殖细胞核抗原加载到DNA上。它是AAA+(与各种细胞活动相关的ATP酶)ATP酶家族的成员,并与38和40千道尔顿亚基形成核心复合物,该复合物具有依赖于DNA的ATP酶活性。在染色体9上已经发现了相关的假基因。选择性剪接导致多个转录变异体。[由RefSeq,2016年11月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6
11
24746 bp
38.50
16
--
3
9

RFC5 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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