Log In|Sign Up
中文人类
BCL2L1 - BCL2 Like 1
Alias:
BCLX
BCL2L
Bcl-X
PPP1R52
BCL-XL/S
Favorite
这个基因编码的蛋白质属于BCL-2蛋白家族。BCL-2家族成员形成异源或同源二聚体，作为抗凋亡或促凋亡调节因子参与多种细胞活动。这个基因编码的蛋白质位于线粒体外膜上，已显示可以调节线粒体外膜通道(VDAC)的开放。VDAC调节线粒体膜电位，从而控制线粒体产生的活性氧物种和细胞色素C的释放，两者都是细胞凋亡的有效诱导剂。可变剪接导致多个转录变异体，编码两种不同的异构体。较长的异构体作为凋亡抑制剂，较短的异构体作为凋亡激活剂。[RefSeq,2015年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
BCL2L1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
