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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
RELA - RELA Proto-oncogene, NF-kB Subunit
Alias:
p65
CMCU
NFKB3
AIF3BL3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
核因子kappa B是一种普遍存在的转录因子,参与几个生物过程。它在细胞质中被特定的抑制因子保持在非活性状态。在抑制因子降解后,核因子kappa B移至细胞核并激活特定基因的转录。核因子kappa B由与REL、RELA或RELB结合的NFKB1或NFKB2组成。最丰富的核因子kappa B形式是与这个基因的产物RELA结合的NFKB1。已经发现这个基因有四个编码不同异型的转录变异体。[由RefSeq,2011年9月提供]
Related ID:
NCBI:5970
ENSEMBL:ENSG00000173039
HGNC:9955
UNIPROT:Q04206
OMIM:164014
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5970
12
11
10257 bp
60.22
259
4
19
79
RELA Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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Cell-specific RNA expression
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Name
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Status
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Link
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References Literature
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