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Ntrk1 - neurotrophic receptor tyrosine kinase 1

Alias:
Trk
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
使多个功能成为可能,包括GPI连接的Ephrin受体活性;神经生长因子结合活性;以及神经营养素p75受体结合活性。参与多个过程,包括检测与疼痛感知相关的刺激;神经系统发育;以及调控程序性细胞死亡。在细胞对生长因子刺激的细胞内响应和蛋白质自磷酸化过程中发挥上游作用。位于几个细胞组分中,包括树突;内质网;和神经元细胞体。蛋白质复合物的一部分。用于研究青光眼和肌筋膜疼痛综合症。几种疾病的生物标志物,包括结肠炎;糖尿病性神经病变;青光眼;牙周炎;和视网膜脱离。该基因的人类同源物与阿尔茨海默病;遗传性感觉神经病变;遗传性感觉神经病变4型;和精神分裂症有关。与人类NTRK1(神经营养受体酪氨酸激酶1)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
3
17
16846 bp
87.87
26
17

Ntrk1 Genetics information (-)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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