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中文人类
RAP1A - RAP1A, Member Of RAS Oncogene Family
Alias:
RAP1
C21KG
G-22K
KREV1
KREV-1
SMGP21
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这个基因编码Ras家族的小GTP酶成员。编码的蛋白质会根据其与GTP或GDP结合时的构象状态和活性发生变化。这种蛋白质由几种类型的鸟苷酸交换因子(GEFs)激活，并被两类GTP酶激活蛋白(GAPs)抑制。因此，编码蛋白质的激活状态受细胞内GEFs和GAPs水平的平衡影响。该蛋白质调节影响细胞增殖和粘附的信号通路，并可能参与肿瘤恶性。这个基因的假基因位于染色体14和17上。可选的剪接导致多个转录变异体。[由RefSeq提供，2014年5月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
RAP1A Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
