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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Carm1 - coactivator-associated arginine methyltransferase 1
Alias:
Prmt4
m9Bei
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
能够激活多种功能,包括赖氨酸乙酰化组蛋白结合活性;核受体共激活子活性;以及蛋白质精氨酸N甲基转移酶活性。参与多种过程,包括组蛋白H3-R17甲基化;脂肪细胞分化的正向调节;以及细胞内雌激素受体的信号通路调控。在多个过程的上游或内部发挥作用,包括细胞内雌激素受体的信号通路;生长板软骨细胞的增殖调控;以及转录的DNA模板调控。位于细胞质和细胞核中。是RNA聚合酶II转录调节复合物的一部分。在几个结构中表达,包括鳃弓;中枢神经系统;生殖腺;肢芽;和感觉器官。与人类的CARM1(共激活子相关精氨酸甲基转移酶1)有正交同源性。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:59035
ENSEMBL:ENSMUSG00000032185
UNIPROT:Q9WVG6
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
59035
3
16
42601 bp
65.85
11
29
Carm1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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