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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Med12 - mediator complex subunit 12
Alias:
Mopa
OPA-1
230kDa
Tnrc11
Trap230
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活RNA聚合酶II顺式调控区序列特异性的DNA结合活性;染色质结合活性;以及转录共激活子活性。在几个过程的上游或内部发挥作用,包括Wnt信号通路;脊索动物胚胎发育;以及神经胶质细胞发育。是介体复合物的组成部分。在大脑中表达。这个基因的人类同源物涉及FG综合征;平滑肌肉瘤;重度抑郁症;恐惧症;以及综合征性X连锁智力障碍Lujan-Fryns型。与人类的MED12(介体复合物亚基12)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:59024
ENSEMBL:ENSMUSG00000079487
UNIPROT:A2AGH6
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
59024
1
45
24844 bp
244.56
4
6
Med12 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
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Cell-specific RNA expression
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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