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中文人类
RAD51C - RAD51 Paralog C
Alias:
FANCO
R51H3
BROVCA3
RAD51L2
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这个基因是RAD51家族的成员。RAD51家族成员与细菌RecA和酿酒酵母Rad51高度相似，已知它们参与DNA的同源重组和修复。这个蛋白可以与其他RAD51同源基因相互作用，据报道对霍利迪关节解决很重要。这个基因的突变与Fanconi贫血样综合征有关。这个基因是位于染色体17q23区域的四个基因之一，该区域的扩增在乳腺癌肿瘤中频繁发生。扩增过程中这四个基因的过度表达已经被观察到，这表明它们在肿瘤进展中可能发挥作用。可变剪接导致多个转录变异体。[由RefSeq，2013年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
RAD51C Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
