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中文人类
RAD23B - RAD23 Homolog B, Nucleotide Excision Repair Protein
Alias:
P58
HR23B
HHR23B
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这个基因编码的蛋白质是酵母Rad23的两个人类同源蛋白质之一，参与核苷酸切除修复（NER）。该蛋白质被发现在体外特异性补充角质症色素沉着群C（XP-c）细胞提取物的NER缺陷的蛋白质复合物组成部分。该蛋白质还被证明与3-甲基腺嘌呤-DNA糖基化酶（MPG）的核苷酸切除活性相互作用并提高其活性，这表明在碱基切除修复中在DNA损伤识别中发挥作用。该蛋白质含有N-末端泛素样结构域，据报道该结构域与26S蛋白酶体相互作用，因此该蛋白质可能涉及细胞中泛素介导的蛋白水解途径。可变剪接产生多种编码不同异质体的转录变异体。[由RefSeq，2011年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
RAD23B Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
