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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
DNASE2B - Deoxyribonuclease 2 Beta
Alias:
DLAD
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质与DNase II在序列上有很高的相似性,并且在结构上与之相关。DNase II是一种被充分鉴定的核酸内切酶,能够在酸性pH条件下,在没有二价阳离子的情况下催化DNA水解。与在几乎所有组织中表达的DNase II不同,这个基因产品的表达仅限于唾液腺和肺部。这个基因位于染色体1p22.3上,与尿酸酶假基因相邻(且方向相反)。已经描述了这个基因的两个转录变异体,它们编码不同的异构体。[由RefSeq,2008年7月提供]
Related ID:
NCBI:58511
ENSEMBL:ENSG00000137976
HGNC:28875
UNIPROT:Q8WZ79
OMIM:608057
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
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Reference
58511
4
6
16535 bp
41.71
9
--
4
5
DNASE2B Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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