人类

ARHGAP22 - Rho GTPase Activating Protein 22

Alias:
RhoGAP2
RhoGap22
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个GTP酶激活蛋白家族的成员,该成员激活属于RAS小GTP结合蛋白超家族的GTP酶。编码的蛋白质对胰岛素敏感,依赖于激酶Akt,并需要Akt依赖的14-3-3结合蛋白,该蛋白依次结合两个丝氨酸残基。这些相互作用的结果是调节细胞迁移。已发现这个基因的多个转录变异体,编码不同的异构体。[RefSeq提供,2011年12月]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
32
10
226435 bp
76.78
50
--
4
6

ARHGAP22 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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