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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Cldn10 - claudin 10
Alias:
Cldn10a
Cldn10b
D14Ertd728e
6720456I16Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个无内含子的基因编码一个claudin家族的成员。Claudins是整合膜蛋白,是紧密连接丝的组成部分。紧密连接丝作为物理屏障,防止溶质和水分自由通过上皮或内皮细胞片之间的胞间空间。它们还在维持细胞极性和信号传导中起到关键作用。已经发现了六种可变剪接转录变异体,它们编码具有不同第一个细胞外环电荷和具有或不具有第四个跨膜区域的不同的异构体。这些异构体在胞间阴离子或阳离子通透性方面表现出不同的定位和功能。[RefSeq,2010年8月提供]
Related ID:
NCBI:58187
ENSEMBL:ENSMUSG00000022132
UNIPROT:Q9Z0S6
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
58187
6
5
86655 bp
24.70
3
11
Cldn10 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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