人类

PTPRD - Protein Tyrosine Phosphatase Receptor Type D

Alias:
HPTP
PTPD
HPTPD
HPTPDELTA
RPTPDELTA
R-PTP-delta
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是蛋白质酪氨酸磷酸酶(PTP)家族的一员。PTP被认为是调节各种细胞过程的信号分子,包括细胞生长、分化、有丝分裂周期和癌基因转化。这个PTP包含一个细胞外区域、一个单跨膜片段和两个串联的细胞内催化域,因此代表一个受体型PTP。这个蛋白质的细胞外区域由三个Ig样和八个纤连蛋白III型样结构域组成。研究鸡和果蝇的相似基因表明,这个PTP的作用是促进神经突生长,并调节神经元轴突引导。已经报道了这个基因的多个可变剪接转录变异体。在染色体5上已经发现了一个相关的假基因。[由RefSeq,2010年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
55
46
2298757 bp
214.76
101
--
6
7

PTPRD Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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