人类

PTPRA - Protein Tyrosine Phosphatase Receptor Type A

Alias:
LRP
HLPR
PTPA
HEPTP
HPTPA
RPTPA
PTPRL2
HPTPalpha
R-PTP-alpha
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是蛋白质酪氨酸磷酸酶(PTP)家族的一员。PTP被认为是调节各种细胞过程的信号分子,包括细胞生长、分化、有丝分裂周期和癌基因转化。这个PTP包含一个胞外结构域,一个单跨膜片段和两个串联的胞内催化域,因此代表一个受体型PTP。这个PTP已经显示可以脱磷酸化并激活Src家族酪氨酸激酶,并与整合素信号传导、细胞粘附和增殖的调节有关。这个基因的三个可变剪接变异体已经报道,它们编码两种不同的异构体。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
27
24
174486 bp
90.72
63
1
7
17

PTPRA Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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