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中文人类
MARK4 - Microtubule Affinity Regulating Kinase 4
Alias:
MARK4L
MARK4S
MARKL1
PAR-1D
MARKL1L
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这个基因编码微管亲和调节激酶家族的一员。这些蛋白激酶磷酸化微管相关蛋白，并调节稳定和动态微管之间的过渡。编码的蛋白质在整个有丝分裂过程中与中心体相关联，可能涉及细胞周期控制。这个基因的表达可能是癌症的一个潜在标志，编码的蛋白质可能也在阿尔茨海默病中发挥作用。这个基因的假基因位于染色体3的短臂和长臂上。已经观察到这个基因的替代剪接转录变体编码多种异构体。[RefSeq,2010年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MARK4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
