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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PTPN3 - Protein Tyrosine Phosphatase Non-receptor Type 3
Alias:
PTPH1
PTP-H1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是蛋白质酪氨酸磷酸酶(PTP)家族的成员。PTP被认为是调节各种细胞过程的信号分子,包括细胞生长、分化、有丝分裂周期和癌基因转化。这个蛋白质包含一个C端PTP结构域和一个与细胞骨架关联蛋白的band 4.1超家族同源的N端结构域。已经表明,细胞周期调节剂P97是这种PTP的底物,并参与各种与膜相关的功能。还发现这种PTP与适配器蛋白14-3-3β相互作用,并被其调节。已经发现这个基因的几个可变剪接转录变异体,编码不同的异构体。[由RefSeq,2009年2月提供]
Related ID:
NCBI:5774
ENSEMBL:ENSG00000070159
HGNC:9655
UNIPROT:P26045
OMIM:176877
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
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Reference
5774
17
26
162727 bp
103.99
36
1
10
10
PTPN3 Genetics information (-)
GRCh38
Sequence Homology
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* This data comes from NCBI.
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