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中文人类
TSHZ3 - Teashirt Zinc Finger Homeobox 3
Alias:
TSH3
ZNF537
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这个基因编码一个锌指转录因子，可调节发育中泌尿系统的平滑肌细胞分化。与这一功能一致，该基因被失活的小鼠在泌尿系统平滑肌细胞前体中表现出异常的基因表达，并出现包括肾积水在内的肾脏缺陷。编码的转录因子组成一个基因沉默复合物，可抑制caspase表达。该基因表达降低和caspase上调可能与阿尔茨海默病患者病情进展有关。[RefSeq,2016年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TSHZ3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
