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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PREX1 - Phosphatidylinositol-3,4,5-trisphosphate Dependent Rac Exchange Factor 1
Alias:
P-REX1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质作为RHO家族的小GTP结合蛋白(RACs)的鸟苷酸交换因子。已经证明它可以结合并激活RAC1,通过将结合的GDP交换为自由GTP。该编码的蛋白质主要存在于细胞质中,由磷脂酰肌醇-3,4,5-三磷酸和异三聚G蛋白的β-γ亚基激活。[由RefSeq,2008年7月提供]
Related ID:
NCBI:57580
ENSEMBL:ENSG00000124126
HGNC:32594
UNIPROT:Q8TCU6
OMIM:606905
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
57580
6
40
263934 bp
186.20
66
--
4
9
PREX1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
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Mutations
No data available
Transcripts & Proteins
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Transcript
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
Strain of Origin
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No data available
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CAS Number
Status
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Link
No data available
References Literature
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