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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
USP35 - Ubiquitin Specific Peptidase 35
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码泛素特异性蛋白酶C19家族的成员。这些脱泛素化酶(DUBs)催化从其他蛋白质中去除泛素蛋白。编码的蛋白质与极化的线粒体结合,并已显示抑制NF-kappa B激活并延迟PARK2介导的线粒体降解。这个基因的表达被let-7a微小RNA上调,而在人类肿瘤组织中表达降低。[RefSeq,2017年7月提供]
Related ID:
NCBI:57558
ENSEMBL:ENSG00000118369
HGNC:20061
UNIPROT:Q9P2H5
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
57558
6
11
48301 bp
113.41
78
--
3
10
USP35 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
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Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Alphabetical
Cell-specific RNA expression
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Interactions
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Related Mouse Models
Type
Name
MGI
Strain of Origin
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Mutations
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Status
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Link
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References Literature
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